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KY-226

Product Specifications

CAS Number

1621673-53-7

Target

Phosphatase

Applications

Metabolism

Smiles

CCCCCCS (=O) (=O) NC (=O) C1=CC=C (C=C1) CSCC2=CC=C (C=C2) C3=CC=CC=C3

Molecular Formula

C27H31NO3S2

Additionnal Information

KY-226 is a potent, selective, orally active and allosteric inhibitor of protein tyrosine phosphatase 1B (PTP1B) with IC50 of 0.28 μM for human PTP1B activity. KY-226 exerts anti-diabetic and anti-obesity effects by enhancing insulin and leptin signaling, respectively.

Storage Conditions

3 years -20°C powder

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