SB-297006

Product Specifications

CAS Number

58816-69-6

Target

CCR

Applications

GPCR & G Protein

Smiles

CCOC (=O) C (CC1=CC=C (C=C1) [N+] (=O) [O-]) NC (=O) C2=CC=CC=C2

Molecular Formula

C18H18N2O5

Additionnal Information

SB-297006 is an antagonist of C-C chemokine receptor 3 (CCR3) that suppresses antigen-induced accumulation of T (h) 2 as well as eosinophils in the lungs. SB-297006 suppressed CCL11-induced Th2 chemotaxis with IC50 of 2.5 μM.

Storage Conditions

3 years -20°C powder

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