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APD597

Product Specifications

CAS Number

897732-93-3

Synonyms

JNJ-38431055

Target

GPR

Applications

GPCR & G Protein

Smiles

CC1=C (C=CC (=N1) S (=O) (=O) C) NC2=C (C (=NC=N2) OC3CCN (CC3) C (=O) OC (C) C) OC

Molecular Formula

C21H29N5O6S

Additionnal Information

APD-597 (JNJ-38431055) is a potent and selective G protein-coupled receptor 119 (GPR119) agonist with EC50 of 46 nM for hGPR119 and an inhibitor of Cytochrome P450 2C9 (CYP2C9) with IC50 of 5.8 μM. APD-597 (JNJ-38431055) is developed for treating Type 2 diabetes (T2D) .

Storage Conditions

3 years -20°C powder

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