VL285
Product Specifications
CAS Number
1448188-57-5
Target
E3 Ligase
Applications
Ubiquitin
Smiles
CC1=C (SC=N1) C2=CC=C (C=C2) CNC (=O) C3CC (CN3C (=O) C (C (C) C) N4CC5=CC=CC=C5C4=O) O
Molecular Formula
C29H32N4O4S
Additionnal Information
VL285 is a potent VHL ligand that degrades HaloTag7 fusion proteins. Cotreatment with excess VL285, the core VHL ligand from which HaloPROTAC3 is derived, is able to significantly reduce HaloPROTAC3 mediated activity to 50% degradation.
Storage Conditions
3 years -20°C powder
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