Pemigatinib
Product Specifications
CAS Number
1513857-77-6
Synonyms
INCB054828
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
CCN1C2=C3C=C (NC3=NC=C2CN (C1=O) C4=C (C (=CC (=C4F) OC) OC) F) CN5CCOCC5
Molecular Formula
C24H27F2N5O4
Additionnal Information
Pemigatinib is an orally active and selective inhibitor of FGFR with IC50 of 0.4 nM, 0.5 nM, 1.2 nM and 30 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.
Storage Conditions
3 years -20°C powder
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