JNJ 303
Product Specifications
CAS Number
878489-28-2
Target
Potassium Channel
Applications
Transmembrane Transporters
Smiles
CC (C) (C (=O) NC1C2CC3CC1CC (C3) (C2) NS (=O) (=O) C) OC4=CC=C (C=C4) Cl
Molecular Formula
C21H29ClN2O4S
Additionnal Information
JNJ 303 is a potent blocker of the voltage dependent IKs-channel encoded by KCNQ1/KCNE1 with IC50 of 64 nM. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP) .
Storage Conditions
3 years -20°C powder
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