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ICA-110381

Product Specifications

CAS Number

325457-99-6

Target

Potassium Channel

Applications

Transmembrane Transporters

Smiles

C1=CC (=CC=C1C (=O) NC2=CN=C (C=C2) Cl) Cl

Molecular Formula

C12H8Cl2N2O

Additionnal Information

ICA 110381 (Compound 16) is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy. ICA 110381 exhibits KCNQ2/Q3 agonist activity with EC50 of 0.38 μM and KCNQ1 antagonist activity with IC50 of 15 μM, respectively.

Storage Conditions

3 years -20°C powder

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