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BI-409306

Product Specifications

CAS Number

1189767-28-9

Synonyms

SUB 166499

Target

PDE

Applications

Metabolism

Smiles

C1COCCC1N2C3=C (C=N2) C (=O) NC (=N3) CC4=CC=CC=N4

Molecular Formula

C16H17N5O2

Additionnal Information

BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with mean IC50 of 65 nM and 168 nM, respectively. Treatment with BI 409306 increases brain cGMP levels, promotes long-term potentiation, and improves episodic and working memory performance in rodents.

Storage Conditions

3 years -20°C powder

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