BI-409306
Product Specifications
CAS Number
1189767-28-9
Synonyms
SUB 166499
Target
PDE
Applications
Metabolism
Smiles
C1COCCC1N2C3=C (C=N2) C (=O) NC (=N3) CC4=CC=CC=N4
Molecular Formula
C16H17N5O2
Additionnal Information
BI 409306 (SUB 166499) is a potent and selective inhibitor of human and rat PDE9A with mean IC50 of 65 nM and 168 nM, respectively. Treatment with BI 409306 increases brain cGMP levels, promotes long-term potentiation, and improves episodic and working memory performance in rodents.
Storage Conditions
3 years -20°C powder
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