YF-2
Product Specifications
CAS Number
1311423-89-8
Target
Histone Acetyltransferase
Applications
Epigenetics
Smiles
CCOC1=C (C (=CC=C1) OCCN (C) C) C (=O) NC2=CC (=C (C=C2) Cl) C (F) (F) F
Molecular Formula
C20H22ClF3N2O3
Additionnal Information
YF-2 is a highly selective, blood-brain-barrier permeable activator of histone acetyltransferase (HAT) . In In vitro assays, YF-2 has activity versus CBP, PCAF, and GCN5 with EC50 of 2.75 μΜ, 29.04 μΜ and 49.3 μΜ, respectively. YF-2 also increases p300 activity.
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