TMPyP4 tosylate

Product Specifications

CAS Number

36951-72-1

Target

G-quadruplex

Applications

DNA Damage/DNA Repair

Smiles

CC1=CC=C (C=C1) [S] ([O-]) (=O) =O.CC2=CC=C (C=C2) [S] ([O-]) (=O) =O.CC3=CC=C (C=C3) [S] ([O-]) (=O) =O.CC4=CC=C (C=C4) [S] ([O-]) (=O) =O.C[N+]5=CC=C (C=C5) C6=C7C=CC (=N7) C (=C8[NH]C (=C (C9=CC=[N+] (C) C=C9) C%10=NC (=C (C%11=CC=C6[NH]%11) C%12=CC=[N+] (C) C=C%12) C=C%10) C=C8) C%13=CC=[N+] (C) C=C%13

Molecular Formula

C72H66N8O12S4

Additionnal Information

TMPyP4 tosylate (TMP 1363), a quadruplex-specific ligand, inhibits the interaction between G-quadruplex (G4) and IGF-1 (Insulin-like growth factor type I) . TMPyP4 tosylate is also a telomerase inhibitor with antitumor effects.