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Plecanatide

Product Specifications

CAS Number

467426-54-6

Molecular Formula

C65H104N18O26S4

Additionnal Information

Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis.

Storage Conditions

3 years-20°C powder

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