Tebufenozide-d9
Tebufenozide-d9 is the deuterium labeled Tebufenozide (HY-B2054) . Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells[1][2].
Product Specifications
CAS Number
[2469006-89-9]
UNSPSC
12352005
Target
Apoptosis; Insecticide; Isotope-Labeled Compounds; MDM-2/p53
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C(C1=C([2H])C(C([2H])([2H])[2H])=C([2H])C(C([2H])([2H])[2H])=C1[2H])N(C(C)(C)C)NC(C2=CC=C(C=C2)CC)=O
Molecular Formula
C22H19D9N2O2
Molecular Weight
361.53
References & Citations
[1]Muhammad Fiaz, et al. Toxicological and Morphological Effects of Tebufenozide on Anticarsia Gemmatalis (Lepidoptera: Noctuidae) Larvae. Chemosphere. 2018 Dec;212:337-345.|[2]Xiaoqin Yu, et al. Cytotoxic Effects of Tebufenozide in Vitro Bioassays. Ecotoxicol Environ Saf. 2016 Jul;129:180-8.|[3]Xu W, et al. Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environ Toxicol Pharmacol. 2017 Jan;49:89-96.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B2054S/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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