Tebufenozide-d9

Tebufenozide-d9 is the deuterium labeled Tebufenozide (HY-B2054) . Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells[1][2].

Product Specifications

CAS Number

[2469006-89-9]

UNSPSC

12352005

Target

Apoptosis; Insecticide; Isotope-Labeled Compounds; MDM-2/p53

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

O=C(C1=C([2H])C(C([2H])([2H])[2H])=C([2H])C(C([2H])([2H])[2H])=C1[2H])N(C(C)(C)C)NC(C2=CC=C(C=C2)CC)=O

Molecular Formula

C22H19D9N2O2

Molecular Weight

361.53

References & Citations

[1]Muhammad Fiaz, et al. Toxicological and Morphological Effects of Tebufenozide on Anticarsia Gemmatalis (Lepidoptera: Noctuidae) Larvae. Chemosphere. 2018 Dec;212:337-345.|[2]Xiaoqin Yu, et al. Cytotoxic Effects of Tebufenozide in Vitro Bioassays. Ecotoxicol Environ Saf. 2016 Jul;129:180-8.|[3]Xu W, et al. Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environ Toxicol Pharmacol. 2017 Jan;49:89-96.