Oxyclozanide
Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity[1][2][3].
Product Specifications
CAS Number
2277-92-1
UNSPSC
12352005
Hazard Statement
H302, H410
Target
Bacterial; Fungal; Oxidative Phosphorylation; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Oxyclozanide.html
Purity
98.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(Cl)=CC(Cl)=C1O)C2=C(O)C(Cl)=CC(Cl)=C2Cl
Molecular Formula
C13H6Cl5NO3
Molecular Weight
401.46
Precautions
H302, H410
References & Citations
[1]Georgiev B, Gruev A. Efektivnost na levamizole i oxyclozanide sreshtu paramfistomatozata po ovtsete i govedata [Effectiveness of levamisole and oxyclozanide in paramphistomiasis in sheep and cattle]. Vet Med Nauki. 1979;16 (3) :45-51.|[2]Wang W, et al. Acute and Subacute Toxicity Assessment of Oxyclozanide in Wistar Rats. Front Vet Sci. 2019 Sep 6;6:294.|[3]Levinson MR, et al. The in vitro antibacterial activity of the anthelmintic drug oxyclozanide against common small animal bacterial pathogens. Vet Dermatol. 2019 Aug;30 (4) :314-e87.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Schistosome
Available Sizes
Frequently Asked Questions
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