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NIC3

Product Specifications

CAS Number

494830-67-0

Smiles

CC (C) (C) C1=CC=C (OCC (NCCNC (COC2=CC=C (C (C) (C) C) C=C2) =O) =O) C=C1

Molecular Formula

C26H36N2O4

Additionnal Information

NIC3 is a selective inhibitor of nucleus accumbens-associated protein 1 (NAC1), a BTB/POZ domain-containing transcription corepressor overexpressed in cancers. It binds the conserved Leu-90 residue in NAC1's BTB domain, disrupting homodimerization essential for nuclear body formation and stability.

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