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Forodesine

Product Specifications

CAS Number

209799-67-7

Synonyms

BCX-1777; Immucillin-H

Additionnal Information

Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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