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E 2012

Product Specifications

CAS Number

870843-42-8

Additionnal Information

E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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