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L-Asparaginase

Product Specifications

CAS Number

9015-68-3

Synonyms

L-​ASNase

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Additionnal Information

L-Asparaginase (L-ASNase) is a deamidating enzyme that hydrolyzes L-asparagine and L-glutamine, depleting L-asparagine in the blood and bone marrow. It exhibits anti-leukemic effects by inhibiting RNA and DNA synthesis, leading to blastic cell apoptosis, and is used in acute lymphoblastic leukemia (ALL) research and treatment.

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