Ro 31-8220
Product Specifications
CAS Number
125314-64-9
Synonyms
Bisindolylmaleimide IX
Additionnal Information
Ro 31-8220 is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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