Amiloride
Product Specifications
CAS Number
2609-46-3
Synonyms
MK-870
Target
Sodium Channel
Applications
Transmembrane Transporters
Molecular Formula
C6H8ClN7O
Additionnal Information
Amiloride (MK-870) is the first potent inhibitor of epithelial sodium channel (ENaC), inhibiting δβγ ENaC with an IC50 of 2.6 μM. It is also a typical blocker of PC2 (TRPP2) channels and can be used in the research to study Autosomal dominant polycystic kidney disease (ADPKD) .
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