Thalidomide-O-amido-C4-N3
Product Specifications
CAS Number
2098488-36-7
Synonyms
Cereblon Ligand-Linker Conjugates 4, E3 ligase Ligand-Linker Conjugates 18
Additionnal Information
Thalidomide-O-amido-C4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Thalidomide-O-amido-C4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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