Mitoguazone
Product Specifications
CAS Number
459-86-9
Synonyms
Methylglyoxal-bis (guanylhydrazone), MGBG, Methyl-GAG
Target
Apoptosis related
Applications
Apoptosis
Molecular Formula
C5H12N8
Additionnal Information
Mitoguazone (MGBG, Methyl-GAG) is a polyamine analog that disrupts polyamine biosynthesis by inhibiting S-adenosylmethionine decarboxylase (SAMDC) . It induces apoptosis and triggers p53-independent programmed cell death in the MCF7 cell line. It also inhibits the integration of HIV DNA into cellular DNA in both monocytes and macrophages.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1607130-01 48 Well
Human TNFAIP3-interacting protein 1, TNIP1 ELISA Kit
Sign In for Pricing
View Details MBS1607130-02 96 Well
Human TNFAIP3-interacting protein 1, TNIP1 ELISA Kit
Sign In for Pricing
View Details MBS1607130-03 5x 96 Well
Human TNFAIP3-interacting protein 1, TNIP1 ELISA Kit
Sign In for Pricing
View Details MBS1607130-04 10x 96 Well
Human TNFAIP3-interacting protein 1, TNIP1 ELISA Kit
Sign In for Pricing
View Details 