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L-Alanosine

Product Specifications

CAS Number

5854-93-3

Synonyms

NSC-153353, SDX-102

Additionnal Information

L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine (NSC-153353) blocks the common de novo purine biosynthesis pathway and, thereby, inhibits tumor cells with MTAP deficiency.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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