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VU 0240551

Product Specifications

CAS Number

893990-34-6

Additionnal Information

VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) and is selective versus NKCC1. VU 0240551 also inhibits hERG and L-type Ca2+ channels. VU 0240551 attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential and enhances P cell synaptic transmission.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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