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Mardepodect

Product Specifications

CAS Number

898562-94-2

Synonyms

PF-2545920

Target

PDE

Applications

Metabolism

Molecular Formula

C25H20N4O

Additionnal Information

Mardepodect is a potent, orally active, and selective inhibitor of PDE10A with an IC50 of 0.37 nM and >1000-fold selectivity over other phosphodiesterases. It also suppresses microglial activation in LPS-induced neuroinflammation and MPTP-induced Parkinson's disease mouse models.

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