Mardepodect
Product Specifications
CAS Number
898562-94-2
Synonyms
PF-2545920
Target
PDE
Applications
Metabolism
Molecular Formula
C25H20N4O
Additionnal Information
Mardepodect is a potent, orally active, and selective inhibitor of PDE10A with an IC50 of 0.37 nM and >1000-fold selectivity over other phosphodiesterases. It also suppresses microglial activation in LPS-induced neuroinflammation and MPTP-induced Parkinson's disease mouse models.
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