Pyr10
Product Specifications
CAS Number
1315323-00-2
Additionnal Information
Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 μM (IC50 of 13.08 μM for store operated Ca2+ entry in BRL-2H3 cells) . Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1) /Orai1 channels.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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