GN44028
Product Specifications
CAS Number
1421448-26-1
Target
HIF
Applications
Angiogenesis
Molecular Formula
C18H15N3O2
Additionnal Information
GN44028 is a potent and orally active hypoxia inducible factor (HIF) -1α inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. GN44028 can be used in the research of cancers.
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