Noscapine
Product Specifications
CAS Number
128-62-1
Synonyms
(S, R) -Noscapine
Target
Sigma Receptor
Applications
Neuronal Signaling
Molecular Formula
C22H23NO7
Additionnal Information
Noscapine ((S, R) -Noscapine) is an alkaloid derived from the opium poppy (Papaver somniferum) and is a centrally acting antitussive opiate derivative. It is a non-competitive antagonist of the bradykinin B2 receptor. It also exhibits neuroprotection by activating sigma-1 opioid receptors, which help suppress intracellular NO levels and calcium, thereby providing protection against ischemic injury.
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