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MG-115

Product Specifications

CAS Number

133407-86-0

Target

Proteasome

Applications

Proteases

Molecular Formula

C25H39N3O5

Additionnal Information

MG-115 is a potent and reversible inhibitor of proteasomes with ki of 21 nM and 35 nM for the 20S and 26S proteasomes, respectively. It also induces apoptosis in Rat-1 and PC12 cells by selectively inhibiting the chymotrypsin-like activity of the proteasome.
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