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Veliparib dihydrochloride

Product Specifications

CAS Number

912445-05-7

Synonyms

ABT-888 dihydrochloride

Target

PARP

Applications

DNA Damage/DNA Repair

Molecular Formula

C13H16N4O.2ClH

Additionnal Information

Veliparib dihydrochloride is an orally active and potent inhibitor of both PARP-1 and PARP-2 with Kis of 5.2 nM and 2.9 nM, respectively. It exhibit ability to cross the blood-brain barrier and potentiate DNA-damaging agents in preclinical tumor model.

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