Desmosterol
Product Specifications
CAS Number
313-04-2
Target
Liver X Receptor
Applications
Metabolism
Molecular Formula
C27H44O
Additionnal Information
Desmosterol is the immediate unsaturated precursor of cholesterol and the final biosynthetic intermediate in the Bloch pathway and a key activator of liver X receptors (LXR) while inhibiting SREBP to regulate lipid homeostasis. Its reduction promotes mitochondrial ROS production in macrophages and activates the NLRP3 inflammasome exhibiting potential for research in inflammation, metabolism, and cardiovascular diseases.
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