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RGH-857

Product Specifications

CAS Number

2408754-53-8

Molecular Formula

C21H21F3N4O5S 2121345

Additionnal Information

RGH-857 (compound 51) is an orally active positive allosteric modulator (PAM) of the nicotinic α7 acetylcholine (α7 nACh) receptor with an EC50 of 34 nM for human α7 nAChR and demonstrating exceptional potency and efficacy in preclinical models of cognitive impairment.

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