FMC-376
Product Specifications
CAS Number
2925468-57-9
Molecular Formula
C35H33F3N6O2 3533362
Additionnal Information
KRASG12C. It binds covalently to the mutant cysteine at position 12 in KRAS G12C and directly blocks both the ON and OFF conformations of the mutant KRAS protein, leading to a complete and durable blockade of downstream signaling. FMC‐376 exhibits robust anti‐tumor activity in vivo.G12C
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