What is the catalog number for HGC652?

The catalog number for HGC652 is C18348-5mg.

What sizes are available for HGC652?

HGC652 is available in the following size(s): 5 mg.

HGC652 is currently made to order / not held in immediate stock. Contact us for lead time.

HGC652

Product Specifications

CAS Number

3055558-98-7

Target

Molecular Glues

Applications

Others

Smiles

CN (C (C1=CC=C (C2=C (SC) C=C (F) C=C2) C=C1S (=O) (C) =O) =O) CC3CCCCC3

Molecular Formula

C23H28FNO3S2

Additionnal Information

HGC652 functions as a molecular glue by targeting E3 ubiquitin ligase TRIM21. It facilitates the formation of a TRIM21-NUP98 ternary complex, leading to degradation of NUP155 and nuclear pore complex proteins, ultimately resulting in cell death. The compound shows inhibitory effects on the proliferation of various cancer cell lines, with activity dependent on TRIM21 expression levels.