Bireociclib (XZP-3287, CDK4/6-IN-2)
Product Specifications
CAS Number
1800506-48-2
Target
CDK4/6
Applications
Cell Cycle
Smiles
CCN1CCN (CC2=CN=C (NC3=NC=C (F) C (C4=CC (N (C (C) C) C (C) =N5) =C5C (F) =C4) =C3) N=C2) CC1
Molecular Formula
C27H32F2N8
Additionnal Information
CDK4/6-IN-2 is a CDK4 and CDK6 inhibitor obtained from patent US20180000819A1 (Compound 1) . It exhibits IC50 values of 2.7 nM for CDK4 and 16 nM for CDK6.
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