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AD1058

Product Specifications

CAS Number

2907782-78-7

Smiles

O=S (N1C=CC2=C (N3[C@H] (C) COCC3) N=C (C4=C5C (NC=C5) =NC=C4) N=C21) (C) =O

Molecular Formula

C19H20N6O3S

Additionnal Information

AD1058 is an orally bioavailable ATR inhibitor with blood-brain barrier permeability (IC50 = 1.6 nM) . It demonstrates antitumor effects through inhibition of tumor cell proliferation, induction of cell cycle arrest, and promotion of apoptosis. This compound is applicable for studies involving advanced malignancies and brain metastases.

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