AD1058
Product Specifications
CAS Number
2907782-78-7
Smiles
O=S (N1C=CC2=C (N3[C@H] (C) COCC3) N=C (C4=C5C (NC=C5) =NC=C4) N=C21) (C) =O
Molecular Formula
C19H20N6O3S
Additionnal Information
AD1058 is an orally bioavailable ATR inhibitor with blood-brain barrier permeability (IC50 = 1.6 nM) . It demonstrates antitumor effects through inhibition of tumor cell proliferation, induction of cell cycle arrest, and promotion of apoptosis. This compound is applicable for studies involving advanced malignancies and brain metastases.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10361860 96 Well
Monkey Olfactory receptor 51A4 (OR51A4) ELISA Kit
Sign In for Pricing
View Details 