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HRS‐5346

Product Specifications

CAS Number

2924841-79-0

Smiles

O=C (O) [C@H] ([C@H]1CCNC1) CC2=CC=CC (CN (CC3=CC (C[C@H] (C (O) =O) [C@H]4CCNC4) =CC=C3) CCOC5=CC (C[C@H] (C (O) =O) [C@H]6CCNC6) =CC=C5) =C2

Molecular Formula

C43H56N4O7

Additionnal Information

Lp (a) -IN-5 (Compound A) is an orally administered lipoprotein (a) (Lp (a) ) inhibitor. This compound demonstrates inhibition of Apo (a) and ApoB protein assembly with an IC50 of 0.41 nM. It may be useful for studying diseases associated with increased plasma Lp (a) levels, including cardiovascular disorders.

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