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VT3989

Product Specifications

CAS Number

2506273-81-8

Synonyms

YAP/TAZ inhibitor-3

Target

TEAD

Applications

Hippo

Molecular Formula

C21H18F3NO3

Additionnal Information

VT3989 (YAP/TAZ inhibitor-3) is a potent and selective oral inhibitor of TEAD auto-palmitoylation, blocking its interaction with yes-associated protein (YAP) . It exhibits antitumor activity and shows potential for treating mesothelioma and solid tumors with NF2 mutations.

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