VT3989
Product Specifications
CAS Number
2506273-81-8
Synonyms
YAP/TAZ inhibitor-3
Target
TEAD
Applications
Hippo
Molecular Formula
C21H18F3NO3
Additionnal Information
VT3989 (YAP/TAZ inhibitor-3) is a potent and selective oral inhibitor of TEAD auto-palmitoylation, blocking its interaction with yes-associated protein (YAP) . It exhibits antitumor activity and shows potential for treating mesothelioma and solid tumors with NF2 mutations.
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