What is the catalog number for E1231?

The catalog number for E1231 is C15147-1g.

What sizes are available for E1231?

E1231 is available in the following size(s): 1 g.

E1231 is currently made to order / not held in immediate stock. Contact us for lead time.

E1231

Product Specifications

CAS Number

1031195-19-3

Synonyms

1-{4-[2- (5-Methylfuran-2-yl) quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one

Target

Survivin

Applications

Apoptosis

Molecular Formula

C21H21N3O3

Additionnal Information

E1231 (1-{4-[2- (5-Methylfuran-2-yl) quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one) is a piperazine 1,4-diamide compound and an oral activator of SIRT1 with an EC50 of 0.83μM. It increases cholesterol efflux and decreases lipid accumulation in macrophages. E1231 regulates cholesterol and lipid metabolism in hyperlipidemic golden hamsters, with potential for atherosclerosis treatment.