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JY-2

Product Specifications

CAS Number

339103-05-8

Target

FOX

Applications

Metabolism

Molecular Formula

C13H7Cl2N3O

Additionnal Information

JY-2 is a selective and orally active inhibitor of the transcription factor forkhead box O1 (FoxO1) . JY-2 suppresses FoxO1-driven transcriptional activity with an IC50 of 22 μM, and also exerts moderate inhibitory effects on FoxO3a and FoxO4. JY-2 also exhibits anti-diabetic properties.
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