(R) -tamsulosin

(R) -Tamsulosin ((R) - (-) -YM12617 free base, LY253351 free base) is the enantiomerically pure, pharmacologically active form of tamsulosin, a selective α1A-adrenergic receptor antagonist used in the treatment of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) . This form is synthesized using chiral N- (1-phenylethyl) aziridine-2-carboxylate derivatives, which allow for highly stereoselective processes in its production.