What is the catalog number for Tetrabenazine?

The catalog number for Tetrabenazine is C03699-25mg.

What sizes are available for Tetrabenazine?

Tetrabenazine is available in the following size(s): 25 mg.

Is Tetrabenazine in stock?

Tetrabenazine is currently made to order / not held in immediate stock. Contact us for lead time.

Tetrabenazine

Product Specifications

CAS Number

718635-93-9

Synonyms

Ro 1-9569

Target

VMAT

Applications

Transmembrane Transporters

Molecular Formula

C19H27NO3

Additionnal Information

Tetrabenazine (Ro 1-9569) is a non-competitive inhibitor of the vesicular monoamine transporter (VMAT), with a higher selectivity for VMAT2 over VMAT1. It exhibits an IC50 of 0.3 μM for VMAT2 and 3 μM for VMAT1, and a Kd of 60 nM for VMAT2 and 9.38 nM for VMAT1. It treats Huntington’s chorea by reducing excessive dopaminergic activity and impairing monoamine storage in synaptic vesicles.