Domperidone monomaleate
Product Specifications
CAS Number
83898-65-1
Synonyms
R33812 monomaleate
Target
Dopamine Receptor
Applications
Neuronal Signaling
Molecular Formula
C22H24ClN5O2.C4H4O4
Additionnal Information
Domperidone monomaleate (R33812 monomaleate) is a potent antagonist of dopamine D2 receptor that acts as an antiemetic and prokinetic agent by targeting the chemoreceptor trigger zone and motor function of the stomach and small intestine. It also inhibits cardiac Na+ channels such as Nav1.5, suggesting a potential molecular mechanism for cardiovascular side effects like malignant arrhythmias.
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