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Cilastatin sodium

Product Specifications

CAS Number

81129-83-1

Synonyms

MK0791 sodium

Target

Others

Applications

Others

Molecular Formula

C16H26N2O5S.Na

Additionnal Information

Cilastatin sodium (MK0791 sodium) is a reversible, competitive inhibitor of renal dehydropeptidase I (also known as membrane dipeptidase, MDP), with an IC50 of 0.1 μM. It is primarily used in combination with imipenem to enhance the antibiotic's effectiveness against a broad spectrum of bacterial infections by preventing its degradation in the kidneys.
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