Selumetinib sulfate
Product Specifications
CAS Number
943332-08-9
Synonyms
AZD6244 sulfate, ARRY-142886 sulfate
Target
MEK
Applications
Protein Tyrosine Kinase
Molecular Formula
C17H15BrClFN4O3.H2O4S
Additionnal Information
Selumetinib sulfate (AZD6244 sulfate, ARRY-142886 sulfate) is an oral, non-ATP-competitive inhibitor of MEK1/2, with an IC50 of 14 nmol/L against purified MEK1. It exhibits an anti-tumor effect in the HT-29 xenograft model and is used to treat cancer and inflammation.
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