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Selumetinib sulfate

Product Specifications

CAS Number

943332-08-9

Synonyms

AZD6244 sulfate, ARRY-142886 sulfate

Target

MEK

Applications

Protein Tyrosine Kinase

Molecular Formula

C17H15BrClFN4O3.H2O4S

Additionnal Information

Selumetinib sulfate (AZD6244 sulfate, ARRY-142886 sulfate) is an oral, non-ATP-competitive inhibitor of MEK1/2, with an IC50 of 14 nmol/L against purified MEK1. It exhibits an anti-tumor effect in the HT-29 xenograft model and is used to treat cancer and inflammation.

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