Agomelatine hydrochloride
Product Specifications
CAS Number
1176316-99-6
Synonyms
S-20098 hydrochloride
Target
MT Receptor
Applications
Neuronal Signaling
Molecular Formula
C15H17NO2.ClH
Additionnal Information
Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. It is also a selective antagonist of 5-HT2C receptors with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively. Blockade of these receptors enhances adrenergic and dopaminergic transmission in the frontocortical regions.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Lambda Light Chain Mouse Monoclonal Antibody [A8G3]](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80e3d/imageurl/ha601054.webp)
HA601054 100 µL
Lambda Light Chain Mouse Monoclonal Antibody [A8G3]
Sign In for Pricing
View Details ![CD8A Mouse Monoclonal Antibody [Clone ID: C8/468 + C8/144B]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd535/imageurl/am33320pu-s.webp)
AM33320PU-S 100 µg
CD8A Mouse Monoclonal Antibody [Clone ID: C8/468 + C8/144B]
Sign In for Pricing
View Details 
TP308387M 100 µg
Staufen (STAU1) (NM_017453) Human Recombinant Protein
Sign In for Pricing
View Details 
